abstract：:Acute arsenic poisoning is a rare cause of suicide attempt. It causes a multiple organs failure caused by cardiogenic shock. We report the case of a patient admitted twelve hours after an ingestion of trioxide arsenic having survived thanks to a premature treatment. ...

journal_title：Annales de biologie clinique

authors： Montelescaut E,Vermeersch V,Commandeur D,Huynh S,Danguy des Deserts M,Sapin J,Ould-Ahmed M,Drouillard I

更新日期：2014-11-01 00:00:00

abstract：:The full blood count (FBC) is the most prescribed laboratory test in France. Due to the lack of data, there is a great variability in reference values of the FBC, between medical laboratories. The aim of this work was to provide normal reference values for FBC in adults. These normal values were defined in a populatio...

journal_title：Annales de biologie clinique

authors： Troussard X,Vol S,Cornet E,Bardet V,Couaillac JP,Fossat C,Luce JC,Maldonado E,Siguret V,Tichet J,Lantieri O,Corberand J,Groupe francophone d'hématologie cellulaire (GFHC).

更新日期：2014-09-01 00:00:00

abstract：:We evaluated the analytical performances of the SPAPLUS(®) immunoturbidimeter assays manufactured by The Binding Site(®) for the quantification of thirteen immunological parameters in serum: IgG, IgA, IgM and IgD immunoglobulins, IgG subclasses (1 to 4), IgA subclasses (1 and 2), beta-2 microglobulin, free light chain...

journal_title：Annales de biologie clinique

authors： Thevenet I,Benat C,Chauzeix J,Blancher A,Puissant-Lubrano B

更新日期：2014-07-01 00:00:00

abstract：:This paper points out the structural and physiological data of galectin-3, and emphasizes its role in cardiac fibrosis and heart failure pathophysiology. Then we summarize the optimal conditions for sampling, assays and we discuss the interpretation of results. ...

journal_title：Annales de biologie clinique

authors： Desbène C,Gaillard O

更新日期：2014-07-01 00:00:00

abstract：:The multimeric glycoprotein Von Willebrand factor (vWF), is produced by vascular endothelium and platelet. If some constitutionals deficiencies leading to hemorrhagic syndrome have been explored in the literature, increased production of vWF observed during cellular distress and pregnancy have not been explored in our...

journal_title：Annales de biologie clinique

authors： Ewodo S,Nguefack CT,Adiogo D,Etong EM,Beyiha G,Belley PE

更新日期：2014-05-01 00:00:00

abstract：:The identification of a product absorbed by an opiate consumer is sometimes problematic since there is no specific biomarker for all molecules. We developed an ultra-high pressure liquid chromatography coupled to tandem mass spectrometry technique which allows the identification and the quantification of 25 opiates in...

journal_title：Annales de biologie clinique

authors： Dubois N,Counerotte S,Goffin E,Pirotte B,Charlier C

更新日期：2014-03-01 00:00:00

abstract：:We report the case of a 20 years old woman with unusual acute myeloid leukemia t(8;21). Cytological, phenotypic and cytogenetic investigations showed a divergence from those of the literature as well as data for the last 12 LA to t(8;21) supported in the service. ...

journal_title：Annales de biologie clinique

authors： Marinier A,Malfuson JV,Konopacki J,Foissaud V,Samson T

更新日期：2014-01-01 00:00:00

abstract：:S100B is a small protein selectively synthesized by cerebral astroglial cells. S100B participates physiologically in the regulation of intracellular free calcium levels, and exerts a neurotrophic activity on cerebral cells. The interest of S100B protein in clinical biology results from its physiological presence in bi...

journal_title：Annales de biologie clinique

authors： Beaudeux JL,Laribi S

更新日期：2013-11-01 00:00:00

abstract：:Immunophenotyping is a major tool for the diagnosis of the chronic lymphoïd leukaemia (CLL). Its interest remains limited in the classification of the other B chronic lymphoproliférative syndromes (B-CLPS). We evaluate the place of the flow cytometry (CMF) in the diagnosis and classification of the non CLL B-CLPS. The...

journal_title：Annales de biologie clinique

authors： El Borgi W,Ben Salah N,Ben Lakhal F,Makni L,Gouider E,Hafsia R

更新日期：2013-11-01 00:00:00

abstract：:The diagnosis of non ST elevation myocardial infarction (NSTEMI) is very important for the emergency doctor. According to the literature copeptin, a marker of the endogenous stress, combined with troponin could be of interest in this diagnosis. The objective of the study was to investigate the association of high-sens...

journal_title：Annales de biologie clinique

authors： Bourgeois C,Douplat M,Guieu R,Pradel V,Fromonot J,Bonnet JL,Alazia M

更新日期：2013-09-01 00:00:00

abstract：:According to the French legislation on medical biology (January 16th, 2010), all biological laboratories must be accredited according to ISO 15189 for at least 50% of their activities before the end of 2016. The extraction of DNA from a sample of interest, whether solid or liquid is one of the critical steps in molecu...

journal_title：Annales de biologie clinique

authors： Harlé A,Lion M,Husson M,Dubois C,Merlin JL

更新日期：2013-09-01 00:00:00

abstract：:Guanidinoacetate (GAA) and creatine (Cr) are creatine deficiency syndromes (CDS) biochemical markers. We describe a liquid chromatography - tandem mass spectrometry method (LC/MSMS) performing simultaneous analysis of GAA, Cr and creatinine (Crn). Study of Cr uptake by fibroblasts for Cr transporter defect diagnosis i...

journal_title：Annales de biologie clinique

authors： Van Noolen L,Monneret D,Ducros V,Corne C,Lunardi J,Faure P

更新日期：2013-07-01 00:00:00

abstract：:A 58-year-old patient, without any notable medical history, except for alcoholism and treated hypertension, developed anemia and leukopenia with macrocytosis. Folate deficiency was diagnosed and subsequently treated. Despite folate supplementation, the hematological parameters did not normalize. Further diagnosis inve...

journal_title：Annales de biologie clinique

authors： Kouamou E,Stépanian A,Khadra F,de Prost D,Teillet F

更新日期：2013-07-01 00:00:00

abstract：:The aim of this article is to describe the processes involved in the organisation and function of the medical laboratory to fulfill the needs of the users. The knowledge of the different interfaces and relationship is a condition for the control of the processes according to the quality management system. ...

journal_title：Annales de biologie clinique

authors： Daunizeau A,membres du sous-groupe Management de la qualité.

更新日期：2013-06-01 00:00:00

abstract：:This article gives a greed for evaluation of the application in medical laboratory according to requirements of the standard EN ISO 15189 : 2012. This is to allow the responsible of the laboratory to check the requirements of this standard to be applied. ...

journal_title：Annales de biologie clinique

authors： Vassault A,membres du sous-groupe Management de la qualité.

更新日期：2013-06-01 00:00:00

abstract：:French medical laboratories must be accredited before November 2016 according to NF/EN/ISO 15189 standard. However, technical accreditation guidelines cannot be applied literally for the determination of specific IgE for several reasons: more than 600 allergen tests, lack of international gold standard, limited extern...

journal_title：Annales de biologie clinique

authors： Sarrat A,Brabant S,Charbonnier E,Alyanakian MA,Apoil PA,Bienvenu F,Jaby D,Lainé C,Nicaise-Roland P,Renier G,Sainte-Laudy J,Tabary T,Uring-Lambert B,Vigneron C,Lambert C,Groupe de travail du Réseau des biologistes de l'aller

更新日期：2013-05-01 00:00:00

abstract：:Strongyloïdes stercoralis infection is a polymorphic and non specific clinical presentation. Often asymptomatic, it can be not seen. However, in patients with immunodeficiency, high parasite load can be observed, consequence of self-infestation cycle, and can spread throughout the body. This presentation of malignant ...

journal_title：Annales de biologie clinique

authors： Perez P,Debourgogne A,Valloton T,Nani A,Barraud H,Machouart M

更新日期：2013-03-01 00:00:00

abstract：:The evaluation of the effect of ginger on the modulation of toxic effects induced by chromate is the objective of our study. 50 male rats Albinos Wistar were divided to five groups as follow: group I (T) is served as control, received a mineral water by gavage (per os); group II (G) received an experimental diet with ...

journal_title：Annales de biologie clinique

authors： Krim M,Messaadia A,Maidi I,Aouacheri O,Saka S

更新日期：2013-03-01 00:00:00

abstract：:Α 2 antiplasmin congenital deficiency is an uncommun fibrinolysis disorder that is diagnostics after a post-operative surgery. We report two brothers cases of α 2 antiplasmin deficiency diagnosed after a prostadenomectomy bleeding at two years intervals. ...

journal_title：Annales de biologie clinique

authors： Igala M,Oukkach B,Khoubila N,Faez S,Benchekroun S

更新日期：2013-01-01 00:00:00

abstract：:Production of factor VIII or factor IX inhibitors is a major complication limiting the efficiency of substitutive therapy in haemophiliacs. Moreover, viral infections, the second serious complication of replacement therapy, may be associated to the occurrence of antiphospholipid antibodies which paradoxically lead to ...

journal_title：Annales de biologie clinique

authors： Kraiem I,Hadhri S,El Omri H,Sassi R,Chaabani W,Ennabli S,Skouri H

更新日期：2012-11-01 00:00:00

abstract：:The recommended conservative treatment of hyperoxaluria is mainly based on hyperhydration and ingestion of inhibitors of crystallization. In accordance with this context, the aim of this study was to determine the in vitro effect of Hordeum vulgare on calcium oxalate crystallization oxalo-dependent. The crystallizatio...

journal_title：Annales de biologie clinique

authors： Djaroud S,Harrache D,Amar A

更新日期：2012-11-01 00:00:00

abstract：:Iron plays a fundamental role in biology and its concentration in living organisms is regulated very precisely. Many molecules of storage and transportation are used to maintain the intracellular homeostasis. Cancer cells have alterations in this balance. Recent studies have shown that breast cancer cells present abno...

journal_title：Annales de biologie clinique

authors： Durigova A,Jacot W,Pouderoux S,Roques S,Montels F,Lamy PJ

更新日期：2012-07-01 00:00:00

abstract：:Biermer's disease is an autoimmune atrophic gastritis of the fundus predominantly responsible for a malabsorption of vitamin B12. Despite its association with several autoimmune disorders, few observations have reported an association with autoimmune hemolytic anemia (AIHA). We report a case of Biermer's disease assoc...

journal_title：Annales de biologie clinique

authors： Nafil H,Tazi I,Mahmal L

更新日期：2012-07-01 00:00:00

abstract：:We describe the case of a serological reactivation in a Toxoplasma-seropositive subject, following a cardiac transplantation transmitting cysts contained in the myocardial tissue. In a context of acute graft rejection, primary chemoprophylaxis enables to avoid onset of opportunistic toxoplasmosis, emerging with immuno...

journal_title：Annales de biologie clinique

authors： Desoubeaux G,Perret-Gallix K,Machet MC,Sirinelli A,Bailly E,Van Langendonck N,Chandenier J

更新日期：2012-05-01 00:00:00

abstract：:The aim of the present work was to assess the genetic and antigenic variability in the VP1 region of type 3 echviruses (E-3), an enterovirus serotype associated to meningitis, neuro-muscular diseases and type 1 diabetes in human. Forty-six VP1 sequences of E-3, among which 9 were isolated in tunisian infants, were inc...

journal_title：Annales de biologie clinique

authors： Farès W,Rezig D,Yahia AB,Touzi H,Meddeb Z,Triki H

更新日期：2012-03-01 00:00:00

abstract：:This document is a proposal of questionnaire for a self-assessment of the post-examination phase: results validation, reporting and transmitting, post-examination samples keeping and documents archival storage. The questions allow to check that the laboratory fulfils the ISO 15189 Standard and COFRAC SH REF 02 documen...

journal_title：Annales de biologie clinique

authors： Lionne JP,Boutten A,Perrin A,Suiro A,Franck P,Szymanowicz A,membres du sous-groupe post-analytique.

更新日期：2012-02-01 00:00:00

abstract：:Congenital galactosemia is a hereditary, autosomal recessive and metabolic disease. It is linked to an enzyme deficiency, more commonly known by the deficiency of galactose-1- phosphate uridyltransferase (GALT), which is responsible for an accumulation of galactose-1- phosphate in the blood. Clinical symptoms appear e...

journal_title：Annales de biologie clinique

authors： Braham I,Charfeddine B,Ben Othmene L,Neffati S,Mtar A,Ben Abdallah J,Ali Smach M,Dridi H,Limem K

更新日期：2012-01-01 00:00:00

abstract：:The Maroteaux-Lamy disease, or mucopolysaccharidosis type VI is an inherited metabolic disorder severe and rare. It is caused by a deficiency of the enzyme arylsulfatase B. It is characterized by a heterogeneous clinical, radiological and genetic. We report the case of a Maroteaux-Lamy syndrome of in a child aged 7 ye...

journal_title：Annales de biologie clinique

authors： Mtar A,Charfeddine B,Braham I,Ben Abdallah J,Neffati S,Smach MA,Bourfifa Z,Ksouri M,Dridi H,Limem K

更新日期：2011-11-01 00:00:00

abstract：:Circulating citrulline is emerging as an innovating biomarker candidate for assessment of intestinal function. Amino acid synthesized by enterocytes of intestinal mucosal, citrulline is not included in proteins or nutrition products and is a precursor for production of arginine by the kidney. Plasma citrulline is, in ...

journal_title：Annales de biologie clinique

authors： Crenn P,Hanachi M,Neveux N,Cynober L

更新日期：2011-09-01 00:00:00

abstract：:With the general tendency that's to say the grouping of laboratories as technical divisions and the accreditation's obligation, the handling of urinary sample preservation's conditions is a major concern. Urinary sample preservation, with or without boric acid, for UF 1000i urinalysis was the purpose of this study. No...

journal_title：Annales de biologie clinique

authors： Fabbro C,Darolles J,Rault JP

更新日期：2011-09-01 00:00:00

abstract：OBJECTIVE:to develop a rapid and reliable real-time PCR to detect polymorphisms of angiotensinogen (AGT), to compare the two methods of MS-PCR (Mutagenically Separated PCR) and real-time PCR to determine three polymorphisms of the angiotensinogen gene M235T, the A (-6) G and A (-20) C. METHODS:the method of real-time ...

journal_title：Annales de biologie clinique

authors： Dandana A,Gammoudi I,Ferchichi S,Chahed H,Bricca G,Limem HB,Maatouk F,Miled A

更新日期：2011-07-01 00:00:00

abstract：:Anemia is the most common pathology encountered in hematology. Etiologies are numerous, so it is important to adopt a rigorous approach. Complementary examinations must be specific to the clinical situation in order to determine the mechanisms on the one hand and decide the therapeutic management on the other. We repo...

journal_title：Annales de biologie clinique

authors： Roche C,Roche NC,Thefenne H,Saidi R,De Pina JJ,Molinier S,Oliver M

更新日期：2011-05-01 00:00:00

abstract：:Recently, homocysteine and new inflamatory biomarkers are demonstrated to be involved in cardiovascular diseases. These risk factors are not well studied in acute coronary syndrome. We investigated the distribution of homocysteine and inflammatory markers in patients with acute coronary syndrome and evaluated the asso...

journal_title：Annales de biologie clinique

authors： El Oudi M,Bouguerra C,Aouni Z,Mazigh C,Bellaaj R,Machghoul S

更新日期：2011-03-01 00:00:00

abstract：:We have evaluated the methodological quality of the Rémic (microbiology guidelines - bacteriology and mycology) of the Société française de microbiologie (edition2007), using to AGREE criteria, which are consensual at an international level, in particular at the the World Health Organisation (WHO) and at the European ...

journal_title：Annales de biologie clinique

authors： Fonfrède M,Couaillac JP,Augereau C,De Moüy D,Lepargneur JP,Szymanowicz A,Watine J

更新日期：2011-03-01 00:00:00

abstract：:We resume here the guidelines about sample processing and transport for laboratory tests. All the steps of the pre-examination phase process, downstream to the recording of the requests, are described in this document. The purpose is to assure a secure and optimal sample management. The traceability of all the steps o...

journal_title：Annales de biologie clinique

authors： Annette-Reisch M,Soubiran P,Szymanowicz A,membres du sous-groupe 1 pré-analytique.

更新日期：2010-12-01 00:00:00

abstract：:The ISO 15189 standard requires the evaluation of measurement uncertainty where relevant and possible. This document presents recommendations for a simple evaluation of the uncertainty from data available in medical laboratory and illustrates the value of such a determination. ...

journal_title：Annales de biologie clinique

authors： Giroud C,Arnaud J,Vassault A,membres du sous-groupe 2 analytique.

更新日期：2010-12-01 00:00:00

abstract：:Hyperhomocysteinemia is an independent vascular risk factor involved in ischaemic stroke. Aim of this study was to evaluate the prevalence of hyperhomocysteinemia and the role of the metabolic determinants in ischaemic stroke. The study concerned 183 patients in the Department of neurology of the teaching hospital of ...

journal_title：Annales de biologie clinique

authors： Damelan K,Kom A,Kossivi A,Koffi BA,Emile Ak,Kodjo GE

更新日期：2010-11-01 00:00:00

abstract：UNLABELLED:The aim of our study was to evaluate the sensitivity, specificity and predictive values of isolated and combined ASCA and NANA assays in Tunisian inflammatory bowel diseases patients and to assess whether their presence is associated with particular clinical features of the disease. METHODS:128 patients (39...

journal_title：Annales de biologie clinique

authors： Bouzid D,Haddouk S,Amouri A,Ben Haj Hmida Y,Boukthir S,Ben Ayed M,Tahri N,Masmoudi H

更新日期：2010-09-01 00:00:00

abstract：:The discriminatory potency of variable number of tandem repeats (VNTR), based on 7 loci (MIRU 26, 27 and 5 ETRs A, B, C, D, E) was assayed on Mycobacterium bovis strains obtained from samples due to tuberculosis in two slaughterhouses in Algeria. The technique of MIRU-VNTR has been evaluated on 88 strains of M. bovis ...

journal_title：Annales de biologie clinique

authors： Sahraoui N,Muller B,Djamel Y,Fadéla B,Rachid O,Jakob Z,Djamel G

更新日期：2010-07-01 00:00:00

abstract：:This study aims to investigate the prevalence of obesity and overweight and their association with lipid parameters in bipolar patients. Our study included 130 patients with bipolar disorder and 130 control subjects aged respectively 37.9 +/- 12.1 and 37.2 +/- 13.1 years. Obesity was evaluated by body mass index (BMI)...

journal_title：Annales de biologie clinique

authors： Ezzaher A,Haj Mouhamed D,Mechri A,Neffati F,Douki W,Gaha L,Najjar MF

更新日期：2010-05-01 00:00:00